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Diane E Griffin Selected Research

Glutamine (L-Glutamine)

1/2017Glutamine antagonist-mediated immune suppression decreases pathology but delays virus clearance in mice during nonfatal alphavirus encephalomyelitis.
10/2016Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis.
1/2016Alphavirus Encephalomyelitis: Mechanisms and Approaches to Prevention of Neuronal Damage.
4/2015Neurological sequelae induced by alphavirus infection of the CNS are attenuated by treatment with the glutamine antagonist 6-diazo-5-oxo-l-norleucine.

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Diane E Griffin Research Topics

Disease

70Infections
09/2023 - 01/2002
41Measles
01/2023 - 01/2002
23Encephalomyelitis (Myeloencephalitis)
09/2023 - 06/2003
16Virus Diseases (Viral Diseases)
09/2023 - 02/2002
8Alphavirus Infections
01/2021 - 11/2002
8Exanthema (Rash)
01/2020 - 08/2005
7Paralysis (Palsy)
09/2023 - 04/2004
5COVID-19
10/2022 - 12/2020
5Encephalitis (Encephalitis, Rasmussen)
01/2021 - 10/2002
4Coinfection
01/2017 - 04/2002
4Viremia
04/2014 - 08/2005
3Central Nervous System Infections (Central Nervous System Infection)
05/2024 - 03/2006
3Poliomyelitis (Polio)
06/2010 - 10/2006
2Subacute Sclerosing Panencephalitis (SSPE)
01/2020 - 01/2018
2Zika Virus Infection
01/2019 - 01/2017
2Hemorrhage
03/2018 - 01/2018
2Reinfection
01/2018 - 04/2014
2Communicable Diseases (Infectious Diseases)
01/2018 - 01/2012
2Rubella (German Measles)
04/2016 - 11/2007
2Mumps
04/2016 - 11/2007
2Hypersensitivity (Allergy)
07/2010 - 10/2002
2HIV Infections (HIV Infection)
10/2009 - 09/2008
1Melanoma (Melanoma, Malignant)
01/2023
1Chikungunya Fever
12/2022
1Arthritis (Polyarthritis)
01/2021
1Necrosis
01/2019
1Weight Loss (Weight Reduction)
01/2018
1Neoplasms (Cancer)
01/2018
1Congenital Abnormalities (Deformity)
01/2017

Drug/Important Bio-Agent (IBA)

32VaccinesIBA
01/2023 - 04/2003
22Proteins (Proteins, Gene)FDA Link
01/2023 - 02/2002
19RNA (Ribonucleic Acid)IBA
05/2024 - 04/2002
16Viral RNAIBA
01/2022 - 06/2003
12Measles VaccineIBA
01/2018 - 01/2002
11CytokinesIBA
09/2023 - 01/2002
11Antiviral Agents (Antivirals)IBA
09/2023 - 01/2013
10InterferonsIBA
10/2022 - 11/2002
9AntibodiesIBA
01/2022 - 03/2003
8Interleukin-10 (Interleukin 10)IBA
01/2022 - 10/2002
8Interferon-gamma (Interferon, gamma)IBA
01/2020 - 10/2002
7Hemagglutinins (Hemagglutinin)IBA
01/2020 - 09/2003
7Neutralizing AntibodiesIBA
04/2016 - 11/2003
5Immunoglobulin G (IgG)IBA
01/2022 - 11/2007
5Immunoglobulin M (IgM)IBA
03/2018 - 08/2007
5Glutamic Acid (Glutamate)FDA Link
10/2016 - 04/2004
5Formaldehyde (Formol)FDA Link
04/2010 - 01/2002
4HydrolasesIBA
12/2022 - 01/2018
4AntigensIBA
01/2022 - 03/2003
4Interleukin-12 (IL 12)IBA
01/2020 - 01/2002
4Messenger RNA (mRNA)IBA
01/2019 - 01/2013
4InterleukinsIBA
01/2017 - 10/2002
4Glutamine (L-Glutamine)FDA Link
01/2017 - 04/2015
4Interleukin-4 (Interleukin 4)IBA
01/2017 - 01/2002
3Interleukin-6 (Interleukin 6)IBA
01/2023 - 01/2017
3ChemokinesIBA
01/2020 - 10/2016
3DiazooxonorleucineIBA
01/2017 - 04/2015
3propionic acid (potassium propionate)IBA
01/2016 - 04/2004
2Immunologic Factors (Immunomodulators)IBA
09/2023 - 01/2017
2Interferon Regulatory FactorsIBA
09/2023 - 01/2019
2Interleukin-18 (Interleukin 18)IBA
01/2023 - 01/2017
2InflammasomesIBA
01/2023 - 10/2016
2Complement System Proteins (Complement)IBA
01/2022 - 09/2003
2Peptides (Polypeptides)IBA
01/2021 - 06/2007
2EpitopesIBA
11/2019 - 06/2007
2Measles-Mumps-Rubella Vaccine (MMR Vaccine)IBA
04/2016 - 06/2007
2talampanelIBA
01/2016 - 03/2008
2GYKI 52466IBA
01/2016 - 03/2008
2Interferon LambdaIBA
04/2015 - 07/2013
2LipidsIBA
10/2008 - 06/2002
2AMPA Receptors (AMPA Receptor)IBA
03/2008 - 04/2004
2alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
03/2008 - 04/2004
2Inactivated VaccinesIBA
01/2008 - 01/2002
2Immunoglobulins (Immunoglobulin)IBA
06/2007 - 11/2003
1Interferon Regulatory Factor-7 (Interferon Regulatory Factor 7)IBA
09/2023
1NLR ProteinsIBA
01/2023
1PyrinIBA
01/2023
1Caspase 1 (ICE Protease)IBA
01/2023
1phorbol-12-myristateIBA
01/2023
1remdesivirIBA
01/2023
1Adenosine Diphosphate Ribose (ADP-Ribose)IBA
12/2022
1Small Interfering RNA (siRNA)IBA
10/2022
1Poly AIBA
10/2022
1Membrane Proteins (Integral Membrane Proteins)IBA
10/2022
1Antiviral Restriction FactorsIBA
10/2022
1DNA-Directed RNA Polymerases (RNA Polymerase)IBA
01/2022
1Peptide Hydrolases (Proteases)FDA Link
01/2022
1Transforming Growth Factor beta3 (TGF beta 3)IBA
01/2022
1Peptide Initiation Factors (Initiation Factor)IBA
01/2021
1Virulence Factors (Pathogenicity Factors)IBA
01/2021
1Biological FactorsIBA
12/2019
1Prokaryotic Initiation Factor-2IBA
12/2019
1Combined VaccinesIBA
01/2018
1Complementary DNA (cDNA)IBA
01/2018
1ADP-ribosylarginine hydrolaseIBA
01/2018
1Interleukin-2 (IL2)IBA
01/2017
1E 10 (E-10)IBA
01/2017
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2017
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2017
1Nucleocapsid ProteinsIBA
01/2017

Therapy/Procedure

4Therapeutics
01/2022 - 01/2009